![]() It is a biochemical degenerative process that takes place gradually as a result of growing older. Intrinsic aging is also known as chronological aging. Thus, it is important to understand how aging affects the normal physiology of skin. The majority of people aged more than 65 years usually suffer from at least one skin disorder such as xerosis, malignancy, and skin injuries. Other than that, the skin will also undergo changes in parallel with age. This is because the elderly are usually highly dependent as they are more likely to be subjected to age-related diseases. Įven though the increase in life expectancy is very much welcomed by everyone, it can also be considered as an emerging problem. Malaysia is expected to achieve an aging population status by 2035, when 15% of the total population exceeds 60 years old. This is a cause for concern as aging population leads to economic stunting due to shortage of labour and increased cost of healthcare services. Japan has the highest percentage of elderly in their population at 28.2% their population distribution has shifted towards advanced age rather than newborns due to this, as well as reduced fertility. The increasing life expectancy has resulted in an aging population, which is currently a worldwide phenomenon. This is due to the massive improvements in hygiene practice and medical advancement and also increased food supply. In 2019, global life expectancy increased to 73.4 years from 66.8 years in 2000. ![]() The specific age classified as elderly in the third world and developing countries is 60 years old, whereas in the developed countries it is 65 years old. Old age is known as the sunset of life, as the body does not function in the same way that it did when younger. Thus, in this paper, we will be discussing how skin aging occurs and how it can affect the process of wound healing. Even though aging is inevitable, with proper knowledge of skin aging, it may be possible to delay its effects with the help of technological advancements. This has led to an increased effort to study the mechanism of skin aging and how it is related to wound healing. For instance, wound healing, which is a normal physiological response, occurs at a slower rate in aged skin and can usually end up with complications. From a cosmetic point of view, aging also affects the skin’s normal physiological function, as it will not be functioning the same way when aged. Thus, it is easy to understand why aging is a major concern for everyone.Īging is associated with declining health, as it is regarded as a risk factor for most medical conditions, such as cardiovascular diseases, cancers, and physical limitations. No one is exempted from it and, with time, everyone will end up with grey hair, weak joints, wrinkles, and sagging skin or, eventually, might not even be able to recall their own name. Aging is a universal process that we, as human beings, are incapable of slowing down, let alone stopping. However, despite all the accomplishments, there are still some boundaries that we have yet to cross, despite our best efforts. Human civilization has overcome countless obstacles during its long history, mainly through the advancement of knowledge and technology. This shifts the healing process towards having more protein degradation, which can lead to chronic wound healing with an abundance of complications. However, aging has a significant impact on the skin’s healing function by prolonging the inflammatory phase and increasing the production of reactive oxygen species (ROS). Even though skin is subjected to damage by external insults, it is equipped with a healing capability in order to restore its normal structure and function. There are significant morphological changes at all levels in aged skin that have a profound effect on the characteristics of the skin. Extrinsic aging are biochemical processes driven by external influences that lead to aging. Intrinsic aging involves biochemical degenerative processes that gradually takes place with age. Aging of the skin consists of intrinsic and extrinsic processes that work in concert and influence each other. The most striking consequences of aging can be seen visibly on the skin, which acts as a barrier against various external insults. Aging is a universal process that can cause diminished function of organs and various diseases.
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